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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAPK7 All Species: 6.06
Human Site: T594 Identified Species: 10.26
UniProt: Q13164 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13164 NP_002740.2 816 88386 T594 P A P A P A P T P T P T P V Q
Chimpanzee Pan troglodytes XP_511332 494 55249 Y287 L M L S L H E Y T Q A I D L W
Rhesus Macaque Macaca mulatta XP_001099721 816 88521 T594 P A P A P V P T P T P A Q P A
Dog Lupus familis XP_546651 731 80417 R524 R E E K R R R R Q E R A K E R
Cat Felis silvestris
Mouse Mus musculus Q9WVS8 806 87714 A582 M A R P P A P A P A P A P A P
Rat Rattus norvegicus P0C865 806 87808 V580 T R M A R P P V P A P A P A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518277 258 29416 H50 M H S A Q V I H R D L K P S N
Chicken Gallus gallus
Frog Xenopus laevis P26696 361 41238 K154 N V L H R D L K P S N L L L N
Zebra Danio Brachydanio rerio NP_001013469 862 94944 S593 L S S S I S S S N S C P E Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780133 1079 118303 T758 G G G K M P V T A L S R Q R E
Poplar Tree Populus trichocarpa XP_002302599 372 42612 H165 V H S A N V L H R D L K P S N
Maize Zea mays NP_001152745 397 44917 H190 I H S A N V L H R D L K P S N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39024 376 42833 D169 S A N V L H R D L K P S N L L
Baker's Yeast Sacchar. cerevisiae Q00772 484 55617 K277 H Q L G F I P K V P F V N L Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.6 97.6 86.7 N.A. 92 92.1 N.A. 30.3 N.A. 24.1 47.3 N.A. N.A. N.A. N.A. 32.7
Protein Similarity: 100 54.6 98 87.9 N.A. 93.2 93.3 N.A. 31 N.A. 32.8 59.1 N.A. N.A. N.A. N.A. 46.7
P-Site Identity: 100 0 66.6 0 N.A. 46.6 33.3 N.A. 13.3 N.A. 6.6 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 13.3 66.6 6.6 N.A. 46.6 33.3 N.A. 13.3 N.A. 20 40 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: 26.2 26.1 N.A. 25.7 28.8 N.A.
Protein Similarity: 35 35 N.A. 34.6 40.5 N.A.
P-Site Identity: 13.3 13.3 N.A. 13.3 6.6 N.A.
P-Site Similarity: 13.3 13.3 N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 29 0 43 0 15 0 8 8 15 8 29 0 15 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 8 0 22 0 0 8 0 0 % D
% Glu: 0 8 8 0 0 0 8 0 0 8 0 0 8 8 8 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 8 8 8 8 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 22 0 8 0 15 0 22 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 8 8 8 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 15 0 0 0 15 0 8 0 22 8 0 0 % K
% Leu: 15 0 22 0 15 0 22 0 8 8 22 8 8 29 8 % L
% Met: 15 8 8 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 8 0 15 0 0 0 8 0 8 0 15 0 29 % N
% Pro: 15 0 15 8 22 15 36 0 36 8 36 8 43 8 15 % P
% Gln: 0 8 0 0 8 0 0 0 8 8 0 0 15 8 8 % Q
% Arg: 8 8 8 0 22 8 15 8 22 0 8 8 0 8 15 % R
% Ser: 8 8 29 15 0 8 8 8 0 15 8 8 0 22 0 % S
% Thr: 8 0 0 0 0 0 0 22 8 15 0 8 0 0 0 % T
% Val: 8 8 0 8 0 29 8 8 8 0 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _